The production process of traditional Chinese medicine raw materials is relatively complicated: long process, many pipelines, and complicated operations; and most of the preparation raw materials are unstable, such as high environmental parameters such as temperature, humidity, and light, and related raw materials are mostly flammable and explosive. Unlike the preparation product process, the production process of traditional Chinese medicine raw materials is mostly a cross-fusion process of chemical and physical, such as product discoloration, extraction and adsorption. Because the production of traditional Chinese medicine raw materials pays attention to the control of process parameters and environmental parameters, such as light, temperature, and pressure.
The following examples illustrate the different ingredients that can be extracted from the same traditional Chinese medicine ingredients at different temperatures. Such as 1. Add angelica or astragalus powder or angelica and astragalus powder to ethanol, extract at 60~100 ℃ for 1~4h, cool to room temperature, centrifuge to take supernatant, complete one extraction; the number of extraction is 1~4 times. Mix Angelica sinensis with ethanol according to the material ratio of 5~8g/mL, the concentration of ethanol is 40~80wt%, extract at 80 ℃ for 1~2.5h, cool to room temperature, centrifuge and take the supernatant to complete one extraction; extraction times For 1-4 times, extract ferulic acid. 2. Mix Astragalus powder and ethanol according to the material ratio of 12g/mL, the concentration of ethanol is 70wt%, extract at 70 ℃ for 2h, and extract the glycosides. Astragalus powder and ethanol were mixed according to a material ratio of 12g/mL, the concentration of ethanol was 70wt%, and extraction was carried out at 80 °C for 2h to extract flavonoids.
The temperature control unit (TCU) is mainly used for reactor heating and cooling temperature control in the processes of fine chemistry, chemical pharmacy and biopharmaceuticals. It can realize the automatic control of heating, cooling, constant temperature and distillation during the reaction process, especially suitable for the reaction process. There is a process control that requires heat and heat.